Trial design
DOI: 10.4244/EIJ-D-23-00206
Periprocedural continuation versus interruption of oral anticoagulant drugs during transcatheter aortic valve implantation: rationale and design of the POPular PAUSE TAVI trial
Dirk Jan van Ginkel1, MD; Willem L. Bor1, MD; Christophe L.F. Dubois2, MD, PhD; Hugo M. Aarts3,4, MD; Maxim J.P. Rooijakkers5, MD; Kees H. van Bergeijk6, MD; Liesbeth Rosseel7, MD, PhD; Leo Veenstra8, MD; Ole De Backer9, MD, PhD; Nicolas M. Van Mieghem10, MD, PhD; Frank van der Kley11, MD, PhD; Adriaan Wilgenhof3,12, MD; Remigio Leonora13, MD; Jonathan Halim14, MD; Carl E. Schotborgh15, MD, PhD; Emanuele Barbato16, MD, PhD; Jan A.S. Van Der Heyden17, MD, PhD; Peter Frambach18, MD, PhD; Bert Ferdinande19, MD, PhD; Darren Mylotte20, MD, PhD; Enrico Fabris21, MD, PhD; Benno J.W.M. Rensing1, MD, PhD; Leo Timmers1, MD, PhD; Martin J. Swaans1, MD, PhD; Jorn Brouwer1, MD, PhD; Vincent J. Nijenhuis1, MD, PhD; Joyce Peper1, MSc, PhD; Pieter A. Vriesendorp8, MD, PhD; Bas de Laat22, MSc, PhD; Marisa Ninivaggi22, MSc, PhD; Hendrik Stragier23,24, MD; Michiel Voskuil4, MD, PhD; Alexander J.J. IJsselmuiden14, MD, PhD; Renicus S. Hermanides11, MD, PhD; Pierfrancesco Agostoni11, MD, PhD; Arnoud W.J. van 't Hof8,24, MD, PhD; Joanna J. Wykrzykowska6, MD, PhD; Niels van Royen5, MD, PhD; Ronak Delewi3, MD, PhD; Jurrien M. ten Berg1,24, MD, PhD
1. Department of Cardiology, St. Antonius Hospital, Nieuwegein, the Netherlands; 2. Department of Cardiovascular Medicine, University Hospital Leuven, Leuven, Belgium; 3. Department of Cardiology, Amsterdam UMC, Amsterdam, the Netherlands; 4. Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands; 5. Department of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands; 6. Department of Cardiology, University Medical Center Groningen, Groningen, the Netherlands; 7. Department of Cardiology, Algemeen Stedelijk Hospital Aalst, Aalst, Belgium; 8. Department of Cardiology, Maastricht University Medical Center, Maastricht, the Netherlands; 9. The Heart Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; 10. Department of Cardiology, Erasmus University Medical Center, Rotterdam, the Netherlands; 11. Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands; 12. Department of Cardiology, Hospital Network Antwerp (ZNA) Middelheim, Antwerp, Belgium; 13. Department of Cardiology, Isala Hospital, Zwolle, the Netherlands; 14. Department of Cardiology, Amphia Hospital, Breda, the Netherlands; 15. Department of Cardiology, Haga Hospital, The Hague, the Netherlands; 16. Cardiovascular Center Aalst, Onze Lieve Vrouwe Hospital, Aalst, the Netherlands; 17. Department of Cardiology, Sint-Jan Hospital, Brugge, Belgium; 18. Department of Cardiology, Institut National de Chirurgie Cardiaque et de Cardiologie Interventionnelle, Luxembourg City, Luxembourg; 19. Department of Cardiology, Hospital Oost-Limburg, Genk, Belgium; 20. Department of Cardiology, University Hospital Galway, Galway, Ireland; 21. Cardiothoracovascular Department, University of Trieste, Trieste, Italy; 22. Department of Functional Coagulation, Synapse Research Institute, Maastricht, the Netherlands; 23. Department of Anesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Therapy, Hospital Oost-Limburg, Genk, Belgium; 24. Cardiovascular Research Institute Maastricht (CARIM), Maastricht, the Netherlands