1. Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan
The established mechanisms of long-term adverse events related to coronary stenting include thrombosis, neointimal hyperplasia, and persistent inflammation/neoatherosclerosis, which could be closely related to the persistent presence of metallic stents in the vessel wall (Figure 1). Fully bioresorbable vascular scaffolds (BVS) have been developed to overcome the shortcomings of metallic coronary stents that are persistently present with or without polymer in the vessel wall. However, the Absorb™ BVS (Abbott Vascular, Santa Clara, CA, USA) was demonstrated to be inferior to new-generation metallic drug-eluting stents (DES) due to a higher rate of device thrombosis before complete resorption of the ...
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