issue

Jul 21, 2025

Volume 21 Number 14

This issue of EuroIntervention begins with a state-of-the-art on the imaging of atherosclerotic plaques. In original research: results from the highly anticipated 4D-ACS trial on low-dose prasugrel following one-month dual antiplatelet therapy in acute coronary syndrome; and a study on the impact of supersaturated oxygen therapy for acute anterior myocardial infarction patients in relation to microvascular obstruction and infarct size. There are two research correspondences: one which looks at resting pullback pressure gradient (PPG) as an alternative to hyperaemic PPG and the other concerning intracoronary use of nicardipine vs papaverine in the measurement of fractional flow reserve and PPG. There is a viewpoint on the potential of factor XI inhibition; a flashlight discussing anticoagulation for HALT post-TAVI; news from EAPCI; and more...

Viewpoint

Factor XI inhibition for ACS patients: premises and prospects
Lopes R, Fanaroff A
10.4244/EIJ-D-24-00943

State-of-the-Art

Advances in coronary imaging of atherosclerotic plaques
Garcia-Garcia H, Sanz-Sánchez J, Pinilla-Echeverri N, Blanco P, Bourantas C, Alfonso F
10.4244/EIJ-D-24-00387

Original Research

One-month dual antiplatelet therapy followed by prasugrel monotherapy at a reduced dose: the 4D-ACS randomised trial
Jang Y, Park S-D, Lee JP, Choi SH, Kong MG, Won YS, Kim M, Lee KH, Han SH, Kwon SW, Suh J, Kang WC
10.4244/EIJ-D-25-00331

Editorial comment

Impact of intracoronary supersaturated oxygen therapy on microvascular obstruction and infarct size in patients with acute anterior myocardial infarction
König T, Berliner D, Diekmann J, Akin M, Pfeffer T, Sanchez Martinez C, Garcheva V, Bengel F, Bauersachs J, Schäfer A
10.4244/EIJ-D-25-00034

Editorial comment

Research Correspondence

Validation of the pullback pressure gradient in resting conditions
Sakai K, Sonck J, Mizukami T, Matsuo H, Ko B, Perera D, Ando H, Biscaglia S, Rivero F, Leone A, Desta L, Escaned J, Nakayama M, Munhoz D, Storozhenko T, Ohashi H, Campo G, Amano T, Shinke T, Ali Z, De Bruyne B, Johnson N, Collet C, Jeremias A
10.4244/EIJ-D-25-00025
Intracoronary nicardipine to induce hyperaemia
Viscusi M, Seki R, Leone A, Bertolone D, Mizukami T, Mahendiran T, Belmonte M, Sonck J, Collet C, De Bruyne B
10.4244/EIJ-D-25-00068

Flashlight

The heterogeneity of response to direct oral anticoagulants in patients with hypoattenuating leaflet thickening
Husain A, Jelisejevas J, Khoo J, Althekrallah J, Tregobov N, Offen S, Millar K, Leipsic J, Meier D, Sellers S, Webb J
10.4244/EIJ-D-24-00461

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