The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)


The new “tenth commandment”?

EuroIntervention 2016;12:420-421. DOI: 10.4244/EIJV12I4A74

Department of Cardiothoracic Surgery, Guy’s and St. Thomas’ Hospital, London, United Kingdom

Heart valve replacement remains one of the commonest operations performed all over the world and can be regarded as a medical and engineering marvel. However, the search for the perfect solution continues as none of the currently available prostheses satisfies the “10 commandments” set by Dwight Harken in 19621. These are as follows:

1. It must not propagate emboli.

2. It must be chemically inert and not damage blood elements.

3. It must not offer resistance to physiological flow.

4. It must close promptly (less than 0.05 s).

5. It must remain closed during the appropriate phase of the cardiac cycle.

6. ...

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