Sex differences in clinical outcomes following bioresorbable scaffold implantation: a paradigm shift?

EuroIntervention 2019;15:574-576. DOI: 10.4244/EIJV15I7A105

Christos Bourantas
Christos V. Bourantas1,2,3, MD, PhD; Retesh Bajaj1,3, MRCP; Vincenzo Tufaro1, MD; Yakup Kilic1, MD; Patrick W. Serruys4, MD, PhD
1. Barts Heart Centre, Barts Health NHS Trust, London, United Kingdom; 2. Institute of Cardiovascular Sciences, University College London, London, United Kingdom; 3. William Harvey Research Institute, Queen Mary University of London, London, United Kingdom; 4. Faculty of Medicine, National Heart & Lung Institute, Imperial College London, London, United Kingdom

The treatment of female patients with coronary artery disease has traditionally been associated with an increased periprocedural complication rate and worse outcomes compared to male patients. In the early days of plain old balloon angioplasty there was a lower angiographic success rate and a higher complication and mortality rate in women than in men1. The introduction of bare metal stents (BMS) created hopes that this therapy would improve prognosis in this vulnerable population; however, clinical studies and meta-analyses consistently showed worse short-term outcomes in female patients and a higher incidence of death or myocardial infraction at 30-day follow-up2. The ...

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