The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

EDITORIAL

No-reflow after percutaneous coronary intervention: a correlate of poor outcome in both persistent and transient forms

EuroIntervention 2018;14:139-141. DOI: 10.4244/EIJV14I2A21

1. Department of Adult Cardiology, Deutsches Herzzentrum München, Technische Universität, Munich, Germany; 2. DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany


Coronary no-reflow is observed in >20% of patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) and in <2% of patients undergoing elective PCI1. No-reflow typically occurs in the setting of primary PCI after recanalisation of an occluded coronary artery and may be explained by microvascular obstruction caused by ischaemia and reperfusion-related cell injury, which may be exacerbated by intervention-induced distal embolisation of thrombotic material. Nonetheless, no-reflow may also occur following PCI in non-infarct-related arteries (for example, during elective PCI), primarily due to PCI-related distal embolisation of atherosclerotic/thrombotic material leading to microcirculation clogging1. Irrespective ...

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