Clinical research

DOI: 10.4244/EIJ-D-23-00456

Long-term outcomes of measured and predicted prosthesis-patient mismatch following transcatheter aortic valve replacement

Daijiro Tomii1, MD; Taishi Okuno1, MD; Dik Heg2, PhD; Masaaki Nakase1, MD; Jonas Lanz1, MD, MSc; Fabien Praz1, MD; Stefan Stortecky1, MD, MPH; David Reineke3, MD; Stephan Windecker1, MD; Thomas Pilgrim1, MD, MSc

Abstract

Background: Both measured and predicted effective orifice area (EOA) indexed to the body surface area (EOAi) have been suggested to define prosthesis-patient mismatch (PPM) in patients undergoing transcatheter aortic valve replacement (TAVR). The impact of PPM on clinical outcomes may accumulate with extended follow-up and vary according to the definition used.

Aims: We aimed to investigate the long-term clinical impact of PPM in patients undergoing TAVR.

Methods: Patients in a prospective TAVR registry were stratified by the presence of moderate (0.65-0.85 or 0.55-0.70 cm2/m2 if obese) or severe (≤0.65 or ≤0.55 cm2/m2 if obese) PPM according to echocardiographically measured EOAi (measured PPM), predicted EOAi based on published EOA reference values for each valve model and size (predicted PPMTHV), or predicted EOAi based on EOA reference values derived from computed tomography measurements of aortic annulus dimensions (predicted PPMCT).

Results: In an analysis of 2,463 patients, the frequency of measured PPM (moderate: 27.0%; severe: 8.7%) was higher than the frequency of predicted PPMTHV (moderate: 11.3%; severe: 1.2%) or predicted PPMCT (moderate: 12.0%; severe: 0.1%). During a median follow-up of 429...

Sign in to read
the full article

Forgot your password?
No account yet?
Sign up for free!

Create my pcr account

Join us for free and access thousands of articles from EuroIntervention, as well as presentations, videos, cases from PCRonline.com

Volume 19 Number 9
Nov 17, 2023
Volume 19 Number 9
View full issue


Key metrics

On the same subject

Editorial

10.4244/EIJ-E-23-00048 Nov 17, 2023
Patient-prosthesis mismatch following TAVR: time will tell
Thourani V and Holst K
free

Clinical research

10.4244/EIJ-D-23-00011 Jul 17, 2023
Transcatheter aortic valve implantation in patients with extra-small aortic annuli
Tirado-Conte G et al

Clinical Research

10.4244/EIJ-D-21-01091 Aug 5, 2022
Lifetime management of patients with symptomatic severe aortic stenosis: a computed tomography simulation study
Medranda G et al
free

Editorial

10.4244/EIJ-E-22-00021 Aug 5, 2022
Transcatheter or surgical aortic valve replacement in severely obese patients?
Biancari F
free

10.4244/EIJ-E-21-00006 Feb 18, 2022
Valve-in-valve TAVI: the new standard therapy for failing bioprosthetic valves?
Baldus S and Mauri V
free
Trending articles
186.7

State-of-the-Art Review

10.4244/EIJ-D-21-01034 Jun 3, 2022
Management of in-stent restenosis
Alfonso F et al
free
170.15

Translational research

10.4244/EIJ-D-21-00824 May 15, 2022
Bench test and in vivo evaluation of longitudinal stent deformation during proximal optimisation
Toth GG et al
free
159.45

Expert review

10.4244/EIJ-D-21-00690 May 15, 2022
Crush techniques for percutaneous coronary intervention of bifurcation lesions
Moroni F et al
free
127.03

State-of-the-Art

10.4244/EIJ-D-22-00776 Apr 3, 2023
Computed tomographic angiography in coronary artery disease
Serruys PW et al
free
108.75

Viewpoint

10.4244/EIJ-E-22-00007 May 15, 2022
TAVI at 20: how a crazy idea led to a clinical revolution
Eltchaninoff H et al
free
X

The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

EuroPCR EAPCI
PCR ESC
Impact factor: 6.2
2022 Journal Citation Reports®
Science Edition (Clarivate Analytics, 2023)
Online ISSN 1969-6213 - Print ISSN 1774-024X
© 2005-2024 Europa Group - All rights reserved