Keeping it simple but not simpler: the pros and cons of deep sedation versus general anaesthesia for percutaneous mitral valve repair

Since its inception in 2003, percutaneous edge-to-edge mitral valve repair (PMVR) for mitral regurgitation has experienced explosive growth, with >100,000 procedures performed globally to date. The vast majority of these procedures have long been performed with the patient under general anaesthesia (GA); only a disproportionate fraction of patients is being treated under deep sedation (DS).

In this issue of EuroIntervention, Jobs and colleagues present findings from an individual patient data meta-analysis that compared procedural success rate, in-hospital complications, length of hospital stay, and length of intensive care unit (ICU) stay in patients who received either GA or DS during PMVR1.##...