Expert review

A systematic review and meta-analysis of surgical outcomes following mitral valve surgery in octogenarians: implications for transcatheter mitral valve interventions

EuroIntervention 2014;9:1225-1234 published online ahead of print September 2013.

Ali Andalib
Ali Andalib1, MD, MSc; Samuel Mamane1, MD; Ian Schiller2, MSc; Andrea Zakem1, BSc; Darren Mylotte1, MD; Giuseppe Martucci1, MD; Pascal Lauzier1, PhD; Waleed Alharbi1, MD; Renzo Cecere3, MD; Magdalena Dorfmeister4, MD; Ruediger Lange4, MD, PhD; James Brophy2, MD, PhD; Nicolo Piazza1,4* MD, PhD
1. Department of Medicine, Division of Cardiology, Interventional Cardiology, McGill University Health Centre, Montreal, Quebec, Canada; 2. Department of Epidemiology and Biostatistics, McGill University Health Centre, Montreal, Quebec, Canada; 3. Departm

Aims: To evaluate the outcomes of mitral valve surgery in octogenarians with severe symptomatic mitral regurgitation (MR).

Methods and results: We performed a systematic review and meta-analysis of data on octogenarians who underwent mitral valve replacement (MVR) or mitral valve repair (MVRpr). Our search yielded 16 retrospective studies. Using Bayesian hierarchical models, we estimated the pooled proportion of 30-day mortality, postoperative stroke, and long-term survival. The pooled proportion of 30-day postoperative mortality was 13% following MVR (10 studies, 3,105 patients, 95% credible interval [CI] 9-18%), and 7% following MVRpr (six studies, 2,642 patients, 95% CI: 3-12%). Furthermore, pooled proportions of postoperative stroke were 4% (six studies, 2,945 ...

Sign in to read and download the full article

Forgot your password?

No account yet?
Sign up for free!

Create my pcr account

Join us for free and access thousands of articles from EuroIntervention, as well as presentations, videos, cases from

Read next article
First-in-man experience with cryoplasty during graded balloon atrial septostomy to reduce spontaneous closure in a patient with severe pulmonary arterial hypertension

Latest news