The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Procedural and Early Outcomes of Transcatheter Edge-To-Edge Mitral Valve Repair in Very Elderly Patients

DOI: 10.4244/EIJ-D-21-00595

1. University of Arizona College of Medicine Phoenix, Cardiovascular disease, phoenix, AZ - Arizona, United States
2. Department of Cardiovascular disease, John Hopkins hospital, Baltimore, MD,USA;
3. Department of Cardiovascular disease, University of Iowa, Iowa city, IA,USA
4. Department of Cardiovascular disease, Mayo Clinic, Rochester, MN,USA
5. Department of Cardiovascular disease, University of Iowa, Iowa City, IA, USA, United States
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Mitral regurgitation (MR) is a highly prevalent valvular abnormality with an estimated prevalence of 2.1% for moderate to severe degree of MR in population-based studies1.  If untreated, MR leads to significant morbidity and mortality resulting from left ventricular  dilatation and congestive heart failure(CHF)2. Transcatheter mitral valve repair  using MitraClip (Abbott Structural, Menlo Park, California) has revolutionized the treatment of patients with symptomatic severe primary MR who are at a prohibitive risk for surgery and those with symptomatic moderate to severe secondary MR refractory to guideline-directed medical therapy3, 4. Given the association of aging with MR as well as concern for peri-operative mortality and morbidity with open heart surgery, a rising proportion of elderly patients are undergoing MitraClip. However, there are limited data regarding procedural outcomes following MitraClip in elderly patients especially nonagenarians. The objective of this study was to address this knowledge gap using data from a large national database.

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