The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Impact of the CABG SYNTAX Score on 10-year All-cause Death: Insights from the SYNTAX Extended Survival Study

DOI: 10.4244/EIJ-D-20-00170

1. Department of Cardiology, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
2. Department of Cardiothoracic Surgery, Erasmus University Medical Centre, Rotterdam, The Netherlands.
3. Department of Cardiology, Radboud University, Nijmegen, The Netherlands.
4. University Department of Cardiac Surgery, Heart Centre Leipzig, Leipzig, Germany.
5. Département of Cardiologie, Hôpital privé Jacques Cartier, Générale de Santé Massy, France.
6. Department of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, MN, USA.
7. Department of Cardiology, National University of Ireland, Galway (NUIG), Galway, Ireland.
8. Department of Cardiology, National University of Ireland Galway (NUIG), Galway, Ireland, United Kingdom

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The anatomical SYNTAX score (SS) has been considered as an important tool in quantitively assessing the complexity of coronary artery disease (CAD) and in facilitating risk stratification of patients undergoing revascularization. However, the anatomical SS, obtained prior to revascularization, has shown not to be associated with short- and long-term clinical outcomes in patients who received coronary artery bypass grafting (CABG). These findings prompted the development of the CABG SS, assessing native residual stenotic lesions taking into account extent of revascularization by bypass graft, with the Aims:to help identify patients at higher risk of future adverse events. The primary report of the CABG SS assessed at 15 months after surgical revascularization in 115 patients enrolled in the SYNTAX-LE MANS sub-study demonstrated its feasibility (98.3%, n=113) and reproducibility of the score 1 and evaluated  clinical outcomes up to 5 years.

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