The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)


Do the results of the SYNTAX trial apply to my centre?

EuroIntervention 2017;13:781-783. DOI: 10.4244/EIJV13I7A114

University of Ottawa Heart Institute, Ottawa, Ontario, Canada

In 2009, Serruys et al published the SYNergy Between PCI With TAXUS and Cardiac Surgery (SYNTAX) trial in which 1,800 patients with left main or three-vessel coronary artery disease (CAD) were randomly assigned to undergo coronary artery bypass surgery (CABG) or percutaneous coronary intervention (PCI) to determine if PCI performed with drug-eluting stents (DES) was non-inferior to CABG1. The trial was a prospective randomised trial conducted in 85 sites and in 17 countries in Europe and the USA. The primary endpoint was a composite of major adverse cardiac and cerebrovascular events (MACCE), defined as death from any cause, stroke, myocardial infarction, or repeat ...

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