Coronary interventions

Outcomes of rotational atherectomy versus modified balloon angioplasty in severely calcified coronary lesions based on target lesion location: a post hoc analysis of the PREPARE-CALC randomised trial

EuroIntervention 2020;16:e322-e324. DOI: 10.4244/EIJ-D-19-00488

Tobias Rheude
Tobias Rheude1, MD; Ralph Toelg2, MD; Robert A. Byrne3,4, BCh, PhD, MB; Abdelhakim Allali2, MD; Jens Wiebe1, MD; Dmitriy S. Sulimov5, MD; Felix Voll1, MD; Salvatore Cassese1, MD, PhD; Gert Richardt2, MD; Adnan Kastrati1,6, MD; Mohamed Abdel-Wahab5, MD
1. Deutsches Herzzentrum, Munich, Germany; 2. Heart Center, Segeberger Kliniken, Bad Segeberg, Germany; 3. Dublin Cardiovascular Research Institute, Mater Private Hospital, Dublin, Ireland; 4. School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland; 5. Heart Center Leipzig at the University of Leipzig, Leipzig, Germany; 6. DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany

Percutaneous coronary intervention (PCI) of calcified coronary lesions remains a challenge in routine clinical practice. Optimal lesion preparation prior to stent implantation is essential in this lesion subset1. The randomised PREPARE-CALC (The Comparison of Strategies to PREPARE Severely CALCified Coronary Lesions) trial demonstrated superiority for a strategy of lesion preparation with rotational atherectomy (RA) prior to drug-eluting stent (DES) implantation compared to a modified balloon (MB) angioplasty strategy2. As lesion location may have an important influence on device deliverability and strategy success, the aim of this sub-analysis was to investigate the interaction between treatment effect and lesion location.##...

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Coronary interventionsOther coronary interventions
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