The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

10-year outcomes from a randomized comparison of zotarolimus-eluting and sirolimus-eluting stents: the SORT OUT III study

DOI: 10.4244/EIJ-D-19-00503

1. Department of Cardiology, Aarhus University Hospital, Skejby, Aarhus, Denmark, Denmark
2. Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
3. Department of Cardiology, Aarhus University Hospital, Skejby, Aarhus, Denmark
4. Department of Cardiology, Odense University Hospital, Odense, Denmark
5. Department of Cardiology, Aarhus University Hospital, Skejby, Aarhus, Denmark
6. Department of Cardiology, Aarhus University Hospital, Skejby, Aarhus, Denmark
7. Department of Cardiology, Odense University Hospital, Odense, Denmark
8. Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark
9. Department of Cardiology, Aarhus University Hospital, Skejby, Aarhus, Denmark
10. Department of Cardiology, Aarhus University Hospital, Skejby, Aarhus, Denmark
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Previous studies raised concerns about possibly increased risks of early stent thrombosis and target lesion revascularization with the EndeavorÒ Sprint zotarolimus-eluting stent (ZES; Medtronic, Minneapolis, MN) when compared with the CypherÔ Select Plus sirolimus-eluting stent (SES; Cordis, Johnson & Johnson, New Brunswick, NJ). As these differences appeared to diminish over time, a potential reversal of their safety profiles with prolonged follow-up was suggested. The purpose of this study was to examine 10-year outcomes in patients who received ZES versus SES in the Scandinavian Organization for Randomized Trials with Clinical Outcome (SORT OUT) III trial.

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