The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Coronary interventions

Ten-year outcomes from a randomised comparison of zotarolimus-eluting and sirolimus-eluting stents: the SORT OUT III study

EuroIntervention 2019;15:e1022-e1024. DOI: 10.4244/EIJ-D-19-00503

1. Department of Cardiology, Aarhus University Hospital, Skejby, Aarhus, Denmark; 2. Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; 3. Department of Cardiology, Odense University Hospital, Odense, Denmark; 4. Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark


Introduction

Previous studies have raised concerns about the possible increased risks of early stent thrombosis and target lesion revascularisation with the Endeavor® Sprint zotarolimus-eluting stent (ZES; Medtronic, Minneapolis, MN, USA) when compared with the CYPHER Select® Plus sirolimus-eluting stent (SES; Cordis, Johnson & Johnson, Warren, NJ, USA)1,2. As these differences appeared to diminish over time, a potential reversal of their safety profiles with prolonged follow-up was suggested1,2. The purpose of this study was to examine 10-year outcomes in patients who received ZES versus SES in the Scandinavian Organization for Randomized Trials with Clinical Outcome (SORT OUT) ...

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