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DOI: 10.4244/EIJ-D-22-00747

Transcatheter aortic valve implantation of a novel system for severe pure native aortic regurgitation in a patient with an ascending aorta aneurysm

Hendrik Wienemann1, MD; Hesham Elzomor2, MD; Elmar Kuhn3, MD; Jan-Malte Sinning4, MD; Stephan Baldus1, MD; Patrick W. Serruys2, MD, PhD; Matti Adam1, MD

According to the Euro Heart Survey II on valvular heart disease1, 7.4% of patients with single left-sided valve heart disease have native aortic regurgitation (AR). AR is often accompanied by an aneurysm or dilatation of the ascending aorta. In these conditions transcatheter aortic valve implantation (TAVI) remains a therapeutic challenge, since the absence of aortic valve calcification can result in inadequate anchoring of the stent frame, which could therefore result in subsequent valve embolisation or relevant paravalvular regurgitation2.

The JenaValve Trilogy (JenaValve) is a self-expanding valve with a supra-annular porcine valve sutured on a nitinol stent. In May 2021, it became the first device to receive the European Conformity (CE) mark, approving it for use in patients with AR. The key features of the JenaValve Trilogy System are the 3 radial locators that align the valve with the native aortic valve cusps. This locator-dependent anatomical alignment limits protrusion into the left ventricular outflow tract and the left ventricle.

An 83-year-old, highly symptomatic female patient with severe AR and high surgical risk was scheduled for TAVI by the local heart...

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Volume 18 Number 17
Apr 24, 2023
Volume 18 Number 17
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