Image – Interventional flashlight

DOI: 10.4244/EIJ-D-22-00747

Transcatheter aortic valve implantation of a novel system for severe pure native aortic regurgitation in a patient with an ascending aorta aneurysm

Hendrik Wienemann1, MD; Hesham Elzomor2, MD; Elmar Kuhn3, MD; Jan-Malte Sinning4, MD; Stephan Baldus1, MD; Patrick W. Serruys2, MD, PhD; Matti Adam1, MD

According to the Euro Heart Survey II on valvular heart disease1, 7.4% of patients with single left-sided valve heart disease have native aortic regurgitation (AR). AR is often accompanied by an aneurysm or dilatation of the ascending aorta. In these conditions transcatheter aortic valve implantation (TAVI) remains a therapeutic challenge, since the absence of aortic valve calcification can result in inadequate anchoring of the stent frame, which could therefore result in subsequent valve embolisation or relevant paravalvular regurgitation2.

The JenaValve Trilogy (JenaValve) is a self-expanding valve with a supra-annular porcine valve sutured on a nitinol stent. In May 2021, it became the first device to receive the European Conformity (CE) mark, approving it for use in patients with AR. The key features of the JenaValve Trilogy System are the 3 radial locators that align the valve with the native aortic valve cusps. This locator-dependent anatomical alignment limits protrusion into the left ventricular outflow tract and the left ventricle.

An 83-year-old, highly symptomatic female patient with severe AR and high surgical risk was scheduled for TAVI by the local heart...

Sign in to read
the full article

Forgot your password?
No account yet?
Sign up for free!

Create my pcr account

Join us for free and access thousands of articles from EuroIntervention, as well as presentations, videos, cases from

Volume 18 Number 17
Apr 24, 2023
Volume 18 Number 17
View full issue

Key metrics

On the same subject

Image – Interventional flashlight

10.4244/EIJ-D-22-00596 Apr 24, 2023
Treatment of severe aortic valve regurgitation with the Trilogy TAVI system
Yokoyama H et al


10.4244/EIJ-D-16-00347 Feb 3, 2017
Annulus rupture post transcatheter aortic valve implantation complicated by a giant pseudoaneurysm
Thimon T et al

Research correspondence

10.4244/EIJ-D-22-00740 Apr 24, 2023
Procedural considerations for transcatheter aortic valve-in-valve implantation in a degenerated ACURATE neo prosthesis
Vanhaverbeke M et al


10.4244/EIJ-D-17-00567 Sep 24, 2017
Transcatheter aortic valve implantation in 2017: state of the art
Barbanti M et al

10.4244/EIJV11SWA33 Sep 17, 2015
Transfemoral TAVI devices: design overview and clinical outcomes
Abdel-Wahab M et al

Image – Interventional flashlight

10.4244/EIJ-D-19-00690 Aug 28, 2020
Transcatheter aortic valve implantation after transcatheter mitral valve implantation
Kuhn E et al
Trending articles


10.4244/EIJ-D-22-00776 Apr 3, 2023
Computed tomographic angiography in coronary artery disease
Serruys PW et al


10.4244/EIJ-E-22-00007 May 15, 2022
TAVI at 20: how a crazy idea led to a clinical revolution
Eltchaninoff H et al

Expert consensus

10.4244/EIJ-E-22-00018 Dec 4, 2023
Definitions and Standardized Endpoints for Treatment of Coronary Bifurcations
Lunardi M et al

State of the art

10.4244/EIJ-D-22-00969 Jun 19, 2023
Functional coronary angiography for the assessment of the epicardial vessels and the microcirculation
Faria D et al

Clinical research

10.4244/EIJ-D-22-00621 Feb 20, 2023
Long-term changes in coronary physiology after aortic valve replacement
Sabbah M et al

The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

Impact factor: 6.2
2022 Journal Citation Reports®
Science Edition (Clarivate Analytics, 2023)
Online ISSN 1969-6213 - Print ISSN 1774-024X
© 2005-2024 Europa Group - All rights reserved