The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)


Three-year follow-up of the randomised comparison between an everolimus-eluting bioresorbable scaffold and a durable polymer everolimus-eluting metallic stent in patients with ST-segment elevation myocardial infarction (TROFI II trial)

EuroIntervention 2018;14:e1224-e1226 published online November 2018 published online e-edition December 2018. DOI: 10.4244/EIJ-D-18-00839

1. Amsterdam University Medical Center, Amsterdam, the Netherlands; 2. Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands; 3. Complejo Hospitalario Universitario, Hospital Alvaro Cunqueiro, Vigo, Spain; 4. Department of Cardiology, Odense University Hospital, Odense C, Denmark; 5. Bellvitge University Hospital, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, Barcelona, Spain; 6. Department of Cardiology, Medical Centre Leeuwarden, Leeuwarden, the Netherlands; 7. Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; 8. Department of Cardiology, St. Antonius Hospital, Nieuwegein, the Netherlands; 9. Hospital Clinic, Institut Clinic Cardiovascular, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain; 10. Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; 11. NHLI, Imperial College London, London, United Kingdom

Previous midterm follow-up reports after implantation of the Absorb™ everolimus-eluting bioresorbable scaffold (BRS; Abbott Vascular, Santa Clara, CA, USA) in stable coronary artery disease and acute coronary syndrome have shown an increase of scaffold thrombosis leading to an excess of the device-oriented composite endpoint (DOCE: a composite of cardiac death, target vessel myocardial infarction [TVMI], and clinically driven target lesion revascularisation [CD-TLR])1. In contrast, in the six-month primary report of ABSORB STEMI: the TROFI II Study (NCT01986803)2, which randomised patients with ST-elevation myocardial infarction (STEMI) to receive either the Absorb BRS or the XIENCE metallic everolimus-eluting stent (EES; Abbott Vascular), optical frequency domain imaging (OFDI)-derived healing score was comparable between the BRS arm and the EES arm. The aim of this report was to present the three-year clinical outcome results of the BRS and the metallic EES at the time when full resorption of the scaffold device can be expected.

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