The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Clinical outcomes of everolimus-eluting bioresorbable scaffolds or everolimus-eluting stents in patients with acute myocardial infarction: two-year results of the randomised ISAR-Absorb MI trial

DOI: 10.4244/EIJ-D-21-00653

1. Deutsches Herzzentrum München, Department of Cardiology, Technische Universität München, Munich, Germany; 2. DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany; 3. Cardiovascular Research Institute, Mater Private Hospital, Dublin, Ireland; 4. School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, Dublin, Ireland; 5. Cardiac Department, Hospital Universitario de La Princesa Madrid, Madrid, Spain; 6. Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; 7. Clinic and Policlinic Internal Medicine I (Cardiology and Angiology), Klinikum rechts der Isar, Technische Universität München, Munich, Germany; 8. E.N. Meshalkin National Medical Research Center, Novosibirsk, Russia
Introduction

In patients with stable coronary artery disease, drug-eluting bioresorbable scaffolds (BRS) displayed inferior clinical results in comparison to metallic drug-eluting stents1. However, initial evidence on BRS implantation in patients with acute myocardial infarction (AMI) was encouraging (Sabaté M. Biodegradable scaffolds in STEMI: rationale, registry outcomes and TROFI II 2-year results. Presented at Transcatheter Therapeutics (TCT). Washington, DC, Oct 31, 2016) and lends support to further investigation. The Intracoronary Scaffold Assessment a Randomized evaluation of Absorb in Myocardial Infarction (ISAR-Absorb MI) trial demonstrated that BRS implanted in the setting of AMI have a similar antirestenotic efficacy compared to everolimus-eluting stents (...

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