The MITRA-FR study: design and rationale of a randomised study of percutaneous mitral valve repair compared with optimal medical management alone for severe secondary mitral regurgitation

Jean-François Obadia1,2*, MD, PhD; Xavier Armoiry3,4, PharmD, PhD; Bernard Iung5, MD, PhD; Thierry Lefèvre6, MD; Nathan Mewton7, MD, PhD: David Messika-Zeitoun5, MD, PhD; Bertrand Cormier6, MD; Julien Berthiller3, MSc; Delphine Maucort-Boulch8, MD, PhD; Florent Boutitie8, PhD; Bernadette Vaz7, PharmD, MSc; Jean-Noël Trochu9, MD, PhD; Alec Vahanian5, MD, PhD