The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Part II – Debates

Late loss in a disappearing frame of reference: is it still applicable to fully absorbable scaffolds?

EuroIntervention Supplement (2009) Vol. 5 (Supplement F) F43-F48.

Department of Medicine, Division of Cardiovascular Medicine, Brigham and Women’s Hospital and Harvard Clinical Research Institution, Boston, MA, USA

There has been a rapid development in invasive strategies for coronary artery disease from balloon angioplasty alone (no scaffolds) to bare metal stents and drug eluting stents (permanent scaffolds) to bioabsorbable stents (temporary scaffolds). While the introduction of durable stents (permanent scaffolds) resolved issues relating to arterial recoil, restenosis was overcome (to a greater extent) by including drugs to suppress neointimal hyperplasia. Bioabsorbable stents are temporary scaffolds which disappear over a period of time and may also incorporate drug-elution characteristics. We review how the interaction of the mechanical and biological forces in bioabsorbable stents differs from durable stents. ##...

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