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First-in-man Portico® transcatheter aortic valve-in-valve implantation in a degenerated 19 mm Mitroflow® aortic pericardial heart valve

EuroIntervention 2014;9:1368 published online ahead of print February 2014. DOI: 10.4244/EIJV9I11A229

1. Department of Cardiology, University Hospital Basel, Basel, Switzerland; 2. The Heart Centre, Royal Victoria Hospital, Belfast, United Kingdom
A 79-year-old woman was admitted with dyspnoea NYHA Class III to IV. Five years previously, she had undergone surgical aortic valve replacement (Mitroflow® 19 mm; Sorin S.p.A., Milan, Italy). Transthoracic echocardiography revealed a degenerated bioprosthesis (area 225.7 mm2, perimeter 53.4 mm, area and perimeter derived diameter 17 mm; Figure 1A, Figure 1B) with a severe stenosis (aortic valve area 0.63 cm2), a severe transvalvular and mild paravalvular regurgitation, and a severely reduced left ventricular ejection fraction. Because of her symptomatic valvular heart disease and the high perioperative risk (logistic EuroSCORE 18%), she was referred for transfemoral transcatheter aortic valve-in-valve implantation. Given the specific design ...

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