Fast virtual functional assessment of intermediate coronary lesions using routine angiographic data and blood flow simulation in humans: comparison with pressure wire – fractional flow reserve

Michail I. Papafaklis1,2, MD, PhD, FESC; Takashi Muramatsu3, MD; Yuki Ishibashi3, MD; Lampros S. Lakkas1, MD; Shimpei Nakatani3, MD; Christos V. Bourantas3, MD, PhD; Jurgen Ligthart3, BSc; Yoshinobu Onuma3, MD, PhD; Mauro Echavarria-Pinto4, MD; Georgia Tsirka1, MD; Anna Kotsia5, MD; Dimitrios N. Nikas1, MD, PhD, FESC; Owen Mogabgab5, MD; Robert-Jan van Geuns3, MD, PhD; Katerina K. Naka1, MD, PhD, FESC; Dimitrios I. Fotiadis6, PhD; Emmanouil S. Brilakis5, MD, PhD; Héctor M. Garcia-Garci

1. Department of Cardiology, Medical School, University of Ioannina, Ioannina, Greece; 2. Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA; 3. Thoraxcenter, Erasmus Medical Centre, Rotterdam

Aims: To develop a simplified approach of virtual functional assessment of coronary stenosis from routine angiographic data and test it against fractional flow reserve using a pressure wi

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computational fluid dynamicsfractional flow reservefunctional assessmentquantitative coronary angiography

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