The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Editorial

Novel approaches to guide complete revascularisation in patients with STEMI and multivessel coronary artery disease

EuroIntervention 2020;15:e1558-e1559. DOI: 10.4244/EIJV15I18A284

1. Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada


Primary percutaneous coronary intervention is the preferred method of reperfusion in patients with ST-segment elevation myocardial infarction (STEMI). These patients often have multivessel coronary artery disease (CAD), which carries a much worse prognosis than patients with single-vessel disease. Recently, the COMPLETE trial definitively established the benefit of a complete revascularisation strategy in patients with STEMI and multivessel CAD1. At a median follow-up of three years, complete revascularisation reduced cardiovascular (CV) death or new myocardial infarction (MI) by 26% compared with the culprit lesion-only strategy (hazard ratio 0.74, 95% CI: 0.60-0.91; p=0.004). In COMPLETE, as in several other trials2,3, an angiography-guided strategy was ...

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