The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)


Early spontaneous reperfusion after acute myocardial infarction: true association with plaque phenotype or simple clinical observation?

EuroIntervention 2021;17:e613-e615. DOI: 10.4244/EIJV17I8A110

1. Deutsches Herzzentrum München, Technical University of Munich, Munich, Germany; 2. DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany; 3. CVPath Institute, Gaithersburg, MD, USA
Acute myocardial infarction (AMI), with its subclassification into non-ST-elevation (NSTEMI) and ST-elevation myocardial infarction (STEMI), remains the most frequent cause of death on a global scale. Early reperfusion of the occluded coronary artery is an established groundbreaking treatment reducing mortality and morbidity in patients suffering AMI1. Extensive knowledge has been gained from seminal autopsy studies to determine the causes of coronary occlusion, which include plaque rupture, erosion, and calcified nodule2; nevertheless, therapeutic options remain limited to early reperfusion utilising coronary stents. Door-to-balloon time is the most critical factor for salvaging myocardium at risk in the setting of coronary thrombosis; however, ...

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