EuroIntervention State-of-the-Art collection 2024-2025

EuroIntervention is pleased to share our collection of State-of-the-Art articles from 2024-2025. Join us in looking back on the past two years of high-level insights on key topics of interventional interest, written by top-tier international experts.

STATE-OF-THE-ART 2025

Transcatheter edge-to-edge repair in secondary mitral regurgitation

A summary of the current evidence supporting mitral transcatheter edge-to-edge repair, focusing on patient selection, devices and periprocedural and long-term outcomes.

Diagnosis, risk stratification, and early management of non-ST-segment elevation acute coronary syndrome

A comprehensive overview of current approaches for the management of patients with non-ST-segment elevation myocardial infarction, focusing on diagnosis, risk stratification, and treatment strategies.

Identification and treatment of calcified nodules in percutaneous coronary intervention

A summary of current knowledge on the identification and management of calcified nodules in percutaneous coronary intervention, with a focus on intravascular imaging and treatment approaches.

Transcatheter treatment of bicuspid aortic valve stenosis

This review summarises current knowledge on classification, treatment strategies and outcomes of bicuspid aortic valve stenosis, with a focus on the role of transcatheter aortic valve implantation.

Antithrombotic therapy in complex percutaneous coronary intervention

A review summarising available evidence on antithrombotic therapy for complex PCI, discussing the type and duration of antithrombotic regimens and antithrombotic management in specific high-risk scenarios.

Advances in coronary imaging of atherosclerotic plaques

A comprehensive assessment of coronary imaging to characterise plaque components and phenotypes, presenting the plaque features associated with clinical events and summarising the evidence on clinical trials that used serial imaging to evaluate the effects of drugs on plaque morphology and progression/regression.

Treatment of patent foramen ovale

This review summarises diagnostic workup, indications for percutaneous closure, procedural details and routine follow-up recommendations for patent foramen ovale.

Management of complications after valvular interventions

A review of current knowledge on the incidence, prevention and treatment of complications following TAVI, transcatheter mitral edge-to-edge repair, and transcatheter mitral valve replacement.

Percutaneous coronary intervention for calcified and resistant lesions

A summary of current knowledge and best practices in the diagnosis and treatment of calcified coronary lesions, also providing key practical considerations and visual algorithms.

Mechanical circulatory support for complex, high-risk percutaneous coronary intervention

This review outlines the evidence base for the use of mechanical circulatory support during percutaneous coronary intervention, particularly focusing on complex high-risk procedures.

STATE-OF-THE-ART 2024

Optical coherence tomography to guide percutaneous coronary intervention

This review summarises the current knowledge on optical coherence tomography (OCT) to guide percutaneous coronary intervention (PCI). In particular, technical aspects, optimal strategies and fields of application of OCT-guided PCI are presented, with a focus on the latest clinical evidence from randomised trials.

Drug-eluting devices for lower limb peripheral arterial disease

An overview of the evidence on the safety and efficacy of different drug-eluting devices for the treatment of lower limb peripheral arterial disease.

Aortic regurgitation: from mechanisms to management

This review provides a summary of current evidence on the management of aortic regurgitation, particularly regarding diagnostic assessment and treatment options, either surgical or percutaneous.

Antithrombotic therapy for transcatheter structural heart intervention

A review of the knowledge on the thrombotic risk associated with transcatheter structural interventions, with an overview of current evidence-based guidelines on antithrombotic therapy and a focus on gaps in evidence and ongoing investigations in the field.

Durability of transcatheter aortic valve implantation

A comprehensive overview on bioprosthetic valve dysfunction and failure following TAVI, including definitions, causes, risk factors, diagnosis, and management, and compares the durability of TAVI versus SAVR.

Renal denervation in the management of hypertension

This review summarises the rationale and available evidence on renal denervation for the management of hypertension, along with procedural considerations and discussion on the role of this technique in current guidelines and consensus statements.

Percutaneous interventions for pulmonary embolism

A comprehensive evaluation of the current evidence on percutaneous interventions for pulmonary embolism, providing guidance to physicians for the selection of appropriate patients and treatments.

Coronary spasm and vasomotor dysfunction as a cause of MINOCA

Current evidence on epidemiology, pathophysiology, management strategies and prognosis of coronary spasm and vasomotor dysfunction are presented and discussed, with a focus on future research directions.

Targeting inflammation in atherosclerosis: overview, strategy and directions

This review aims to explain the mechanisms of inflammation in atherosclerosis, identifies potential biomarkers, discusses available therapeutic options and their strengths and limitations, highlights future advancements, and summarises notable clinical studies.