Interventions for valvular disease and heart failure

Transcatheter mitral valve repair in patients with acute myocardial infarction: insights from the European Registry of MitraClip in Acute Mitral Regurgitation following an acute myocardial infarction (EREMMI)

EuroIntervention 2020;15:1248-1250. DOI: 10.4244/EIJ-D-19-00653

Rodrigo Estévez-Loureiro
Rodrigo Estevez-Loureiro1, MD, PhD; Marianna Adamo2, MD, PhD; Dabit Arzamendi3, MD, PhD; Paolo Denti4, MD, PhD; Xavier Freixa5, MD, PhD; Luis Nombela-Franco6, MD, PhD; Isaac Pascual7, MD, PhD; Bruno Melica8, MD; David Attias9, MD; Ana Serrador10, MD, PhD; Tomas Benito-González11, MD; Andres Iñiguez1, MD, PhD; Felipe Fernández-Vázquez11, MD, PhD; on behalf of EREMMI Investigators
1. Interventional Cardiology Unit, Hospital Álvaro Cunqueiro, Vigo, Spain; 2. Cardiac Catheterization Laboratory, Cardiothoracic Department, Spedali Civili, Brescia, Italy; 3. Interventional Cardiology Unit, Hospital Sant Pau i Santa Creu, Barcelona, Spain; 4. Department of Cardiovascular Surgery, San Raffaele University Hospital, Milan, Italy; 5. nterventional Cardiology Unit, Hospital Clinic, Barcelona, Spain; 6. Interventional Cardiology Unit, Hospital Clinico San Carlos, Madrid, Spain; 7. Interventional Cardiology Unit, Hospital Universitario Central de Asturias, Oviedo, Spain; 8. Serviço de Cardiologia, Centro Hospitalar de Vila Nova de Gaia/Espinho-EPE, Vila Nova de Gaia, Portugal; 9. Department of Cardiology, Centre Cardiologique du Nord, Saint Denis, France; 10. Interventional Cardiology Unit, Hospital Clinico Universitario de Valladolid, Valladolid, Spain; 11. Interventional Cardiology Unit, Complejo Asistencial Universitario de Leon, Leon, Spain


Acute mitral regurgitation (MR) may develop in the setting of an acute myocardial infarction (AMI) as a result of papillary muscle dysfunction or rupture. Acute ischaemic MR without papillary muscular rupture may induce severe MR due to leaflet tethering produced by the sudden onset of regional or global left ventricular dysfunction. This can lead to pulmonary oedema or cardiogenic shock during the acute or subacute phase of the MI1. Although previous experience with the MitraClip® (Abbott Vascular, Santa Clara, CA, USA) for correcting MR following AMI has been reported2, data on consecutive patients treated for this ...

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