INTERVENTIONAL FLASHLIGHT

DOI: 10.4244/EIJ-D-16-00943

Transcatheter mitral annuloplasty to treat residual mitral regurgitation after MitraClip implantation

Karina Brüstle, MD; Maurizio Taramasso*, MD; Shingo Kuwata, MD, PhD; Francesco Maisano, MD

Mitral regurgitation (MR) recurrence after MitraClip® (Abbott Vascular, Santa Clara, CA, USA) implantation has been associated with increased mortality and heart failure. With percutaneous mitral annuloplasty, the combination of leaflet and annular repair may represent the optimal treatment in patients with persistent MR after MitraClip implantation. This report shows that combining MitraClip with Cardioband (Edwards Lifesciences Inc., Irvine, CA, USA) implantation is feasible, safe and could be beneficial for stable long-term outcomes.

An 83-year-old patient presented with severe functional MR (FMR) and retraction of the posterior leaflet in the central part of the valve (P2 region) as well as annular dilatation. A single MitraClip was implanted between the A2 and P2 segments, leading to an instant decrease in MR. However, eight-month follow-up showed a recurrence of severe residual mitral insufficiency with a large medial and lateral jet and dilated left atrium (Panel A, Panel B). Considering that the reason for MR recurrence was annular dilatation, a Cardioband device was implanted on the atrial side of the mitral annulus. Post-interventional echocardiography as well as 3D imaging showed both MitraClip and Cardioband in the correct position, with significant septolateral annular dimension reduction (Panel C-Panel E). No mitral stenosis was observed and the patient was able to be discharged in an improved clinical condition (Moving image 1).

MitraClip implantation has been the treatment of choice for almost 30,000 patients since its clinical introduction1. However, about 20% of patients have significant recurrent MR2. Annular dilatation is most likely the culprit for MR recurrence. Although the final results of the EVEREST II randomised controlled trial (RCT) showed that mitral annular dimensions do not increase at midterm follow-up after MitraClip implantation, surgical experience has shown that recurrence of MR after valve repair is higher in the absence of concomitant annuloplasty3. The Cardioband system has been in use since 2014 with early data promising feasibility and safety4. The combination of MitraClip and Cardioband represents an equivalent to open surgery leaflet repair and annuloplasty, and should be performed in cases of recurrence. In selected cases such as when there is a high risk of recurrence, we believe that a combined interventional procedure should be considered from the start.

Conflict of interest statement

F. Maisano is a consultant for Abbott Vascular/Valtech Cardio. M. Taramasso is a consultant for Abbott Vascular and 4Tech. The other authors have no conflicts of interest to declare.

Supplementary data

Moving image 1. Reduction of mitral regurgitation with a combination of MitraClip and Cardioband.

Supplementary data

To read the full content of this article, please download the PDF.

Moving image 1. Reduction of mitral regurgitation with a combination of MitraClip and Cardioband.

Volume 13 Number 8
Oct 20, 2017
Volume 13 Number 8
View full issue


Key metrics

Suggested by Cory

INTERVENTIONAL FLASHLIGHT

10.4244/EIJ-D-17-00789 Feb 2, 2018
Residual “inter-clip” regurgitation due to a partial detachment, treated with AMPLATZER Vascular Plug II implantation
Danduch L et al
free

EXPERT REVIEW

10.4244/EIJ-D-18-00511 Sep 7, 2018
Transcatheter mitral valve repair: review of the clinical evidence
Taramasso M et al
free

Image – Interventional flashlight

10.4244/EIJ-D-23-00596 Nov 17, 2023
Electrosurgical laceration and stabilisation of three clip devices (ELASTA-Clip) to enable transcatheter mitral valve implantation
Curio J et al

10.4244/EIJV11SWA14 Sep 17, 2015
Transcatheter direct mitral valve annuloplasty: a brief review
Feldman T and Guerrero M
free

MITRAL VALVE INTERVENTIONS

10.4244/EIJV12SYA15 Sep 18, 2016
The Cardioband: strategies for optimal patient selection and optimised results
Maisano F et al
free

10.4244/EIJV11SWA10 Sep 17, 2015
Transcatheter mitral valve repair: a brief review
Barbanti M et al
free

10.4244/EIJV9I5A102 Sep 27, 2013
MitraClip® via direct right atrial access in case of a missing inferior vena cava
Frerker C et al
free
Trending articles
151.43

State-of-the-Art

10.4244/EIJ-D-22-00776 Apr 3, 2023
Computed tomographic angiography in coronary artery disease
Serruys PW et al
free
55.9

Clinical research

10.4244/EIJ-D-22-00621 Feb 20, 2023
Long-term changes in coronary physiology after aortic valve replacement
Sabbah M et al
free
54.9

Expert review

10.4244/EIJ-D-21-01010 Jun 24, 2022
Device-related thrombus following left atrial appendage occlusion
Simard T et al
free
43.75

Clinical Research

10.4244/EIJ-D-21-01091 Aug 5, 2022
Lifetime management of patients with symptomatic severe aortic stenosis: a computed tomography simulation study
Medranda G et al
free
39.95

Clinical research

10.4244/EIJ-D-22-00558 Feb 6, 2023
Permanent pacemaker implantation and left bundle branch block with self-expanding valves – a SCOPE 2 subanalysis
Pellegrini C et al
free
X

The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

EuroPCR EAPCI
PCR ESC
Impact factor: 7.6
2023 Journal Citation Reports®
Science Edition (Clarivate Analytics, 2024)
Online ISSN 1969-6213 - Print ISSN 1774-024X
© 2005-2024 Europa Group - All rights reserved