Interventions for hypertension and stroke

A systematic transoesophageal echocardiography study of suture-mediated percutaneous patent foramen ovale closure

EuroIntervention 2022;18:63-67. DOI: 10.4244/EIJ-D-21-00242

Alessandro Beneduce
Alessandro Beneduce1, MD; Marco Bruno Ancona1, MD; Francesco Moroni1, MD; Francesco Ancona2, MD; Giacomo Ingallina2, MD; Francesco Melillo2, MD; Filippo Russo1, MD; Luca Angelo Ferri1, MD; Barbara Bellini1, MD; Ciro Vella1, MD; Alaide Chieffo1, MD; Eustachio Agricola2, MD; Matteo Montorfano1, MD
1. Interventional Cardiology Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute, Milan, Italy; 2. Cardiovascular Imaging Unit, Cardio-Thoracic-Vascular Department, IRCCS San Raffaele Scientific Institute, Milan, Italy
Introduction Percutaneous patent foramen ovale (PFO) closure has proven to be superior to medical therapy for secondary prevention in selected patients with cryptogenic stroke1. Furthermore, percutaneous PFO closure prevents decompression sickness and platypnoea-orthodeoxia syndrome, and may play a role in patients with migraine2. However, despite their recognised efficacy, PFO occluders carry a potential risk of early and late complications and may represent an obstacle for future transseptal left-sided catheter-based interventions3. As the vast majority of PFO closure interventions are carried out for preventive purposes in a young population, the concept of “deviceless” PFO closure has become increasingly attractive ...

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