Giulio G. Stefanini1,2, MD, PhD; Marco Vicenzi3,4, MD
1. Humanitas Clinical and Research Hospital IRCCS, Rozzano, Milan, Italy; 2. Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; 3. Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Internal Medicine Department, Respiratory and Cardiovascular Disease Unit, Milan, Italy; 4. Dyspnoea Lab, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
Stent thrombosis (ST) is rare but represents the most dramatic mechanism of coronary stent failure1. In view of the strong association with myocardial infarction (MI) and cardiac death, ST is the primary safety concern of coronary percutaneous coronary interventions (PCI) with stent implantation and represents the key endpoint for the evaluation of the safety profile of coronary stents2.
Evolution of PCI techniques, iterations of stent technologies, and optimisation of medical therapy have markedly reduced the risk of ST1,3. However, a considerable number of patients undergoing PCI with stent implantation still suffer from this life-threatening complication.