The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Second-generation drug-eluting absorbable metal scaffold target-lesion revascularization: an optical coherence tomography case series study and literature review

DOI: 10.4244/EIJ-D-19-00421

1. Hospital Clínic i Provincial de Barcelona, IDIBAPS (Institut d’Investigacions Biomèdiques August Pi i Sunyer), Barcelona, Spain.
2. Hospital Clínic i Provincial de Barcelona, IDIBAPS (Instituto d'investigations Biomédiques August Pi i Sunyer), Barcelona, Spain, Spain
3. Hospital Universitari de Bellvitge, Institut d’ Investigació Biomèdica de Bellvitge (IDIBELL), Universitat de Barcelona, L’Hospitalet de Llobregat, Spain.
4. Cardiology Department, Hospital Clínico Universitario de Valencia, INCLIVA, Departamento de Medicina, Universitat de València, Spain
5. Interventional Cardiology Unit, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain.
6. Departement of Cardiology, Clínica Universidad de Navarra; University of Navarra.
7. Hospital Universitario de La Princesa, Madrid, Spain.
8. Section of Interventional Cardiology, MedStar Cardiovascular Research Network, MedStar Washington Hospital Center, Washington, DC, USA.
9. Hospital Clínic i Provincial de Barcelona, IDIBAPS (Institut d’Investigacions Biomèdiques August Pi i Sunyer), Barcelona, Spain.

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Bioresorbable scaffolds (BRS) were introduced into clinical practice to overcome long-term limitations of drug-eluting stents (DES), but they were instead associated with a high rate of target lesion revascularization (TLR) and thrombosis. Whereas scaffold discontinuity was the most frequent mechanism for polymeric-BRS TLR1, there are no studies on the causes of second-generation drug-eluting absorbable metal scaffold (MgBRS) TLR (Magmaris, BIOTRONIK, Bulach, Switzerland). We sought to determine the optical coherence tomography (OCT) findings in patients who experienced a MgBRS TLR. Moreover, we performed a systematic review of the reported cases.

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