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Periprocedural myocardial infarction in stent trials: how universal is the third universal definition?

EuroIntervention 2016;12:813-817. DOI: 10.4244/EIJV12I7A133

1. Erasmus University Medical Center, Rotterdam, The Netherlands; 2. Heart Institute, University of Sao Paulo Medical School, Sao Paulo, Brazil; 3. Imperial College London, London, United Kingdom

The first criteria for MI definition, used in collaborative projects in the 1970s, were based on the World Health Organization (WHO) European acute MI registry which was later revised in a document published by the WHO together with the International Society and Federation of Cardiology1,2. This definition was based on clinical history, electrocardiographic (ECG) changes (ST-elevation and Q-wave), serum biomarkers and post-mortem findings. In a revised version of the definition, the Minnesota coding was used to standardise ECG criteria3.

This led to a classification of Q-wave and non-Q-wave MIs, used in research protocols and clinical trials. In cases ...

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