The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Percutaneous mitral valve leaflet repair: ongoing directions and future perspectives

DOI: 10.4244/EIJ-D-20-00883

1. Clinic for Cardiac Surgery. University Heart Center Zurich, Rämistrasse 100, CH-8091, Zürich, Switzerland, Switzerland
Disclaimer:

As a public service to our readership, this article - peer reviewed by the Editors of EuroIntervention and external reviewers - has been published immediately upon acceptance as it was received in the last round of revision. The content of this article is the responsibility of the authors.

Please note that supplementary movies are not available online at this stage. Once a paper is published in its edited and formatted form, it will be accompanied online by any supplementary movies.

To read the full content of this article, please log in to download the PDF.

Percutaneous mitral valve leaflet repair has revolutionized the treatment of heart failure patients with secondary mitral regurgitation, as well as it offers a valuable alternative to surgery for high risk patients with degenerative disease. More than one device is now available for leaflet repair, broadening the indications and improving outcomes, as well as complicating the decision-making algorithms. In the last two years, several trials and registries have enriched the evidence around these procedures, although many questions remain open. Two major clinical trials have provided opposing evidence, confirming that this field of cardiovascular medicine remains controversial. Probably, the challenge remains with the human factor: achieving optimal outcomes remains a challenge, highly depending on patient selection, timing and procedural details. Operator dependent factors are emerging as a key element, not unexpectedly, to achieve procedural excellence. Besides large randomized controlled trials, there is a large amount of knowledge emerging from real world registries. The review focus on what we can learn from registries and single center experiences as a complement to the large randomized trials.

Sign in to read and download the full article

Forgot your password?
No account yet? Sign up for free!
Create my pcr account

Join us for free and access thousands of articles from EuroIntervention, as well as presentations, videos, cases from PCRonline.com

Read next article
A mini focus on bifurcation lesions including the Asia Pacific consensus document and a look at the double-kissing culotte technique; left atrial appendage closure compared to medical therapy; assessing aortic regurgitation using video-densitometry, a new classification for the BASILICA technique, and more…