Peripheral interventions

Outcomes of directional atherectomy for common femoral artery disease

EuroIntervention 2021;17:260-266. DOI: 10.4244/EIJ-D-19-00693

Tanja Böhme
Tanja Böhme1, MD; Leonardo Romano2, MD; Roland-Richard Macharzina1, MD; Elias Noory1, MD; Ulrich Beschorner1, MD; Börries Jacques1, MD; Karlheinz Bürgelin1, MD; Peter-Christian Flügel1, MD; Thomas Zeller1, MD; Aljoscha Rastan3, MD
1. Kardiologie und Angiologie II, Universitäts-Herzzentrum Freiburg-Bad Krozingen, Bad Krozingen, Germany; 2. Klinik für Angiologie, Klinikum Hochsauerland, Arnsberg, Germany; 3. Medizinische Uniklinik, Angiologie, Kantonsspital Aarau, Switzerland

Background: Endovascular therapy is the first-line strategy for femoropopliteal obstructive disease. However, for lesions involving the common femoral artery (CFA) surgical endarterectomy is still the gold standard.

Aims: The aim of this study was to evaluate the safety and efficacy of directional atherectomy (DA) for the treatment of CFA lesions.

Methods: A retrospective analysis of patients who underwent DA of the CFA between March 2009 and June 2017 was performed. The primary efficacy endpoint was the incidence of clinically driven target lesion revascularisation (cdTLR). Secondary endpoints included the overall procedural complication rate at 30 days, change in ankle-brachial index (ABI), and Rutherford-Becker class (RBC) during follow-up.

Results: This analysis included 250 patients. The mean follow-up period was 31.03±21.56 months (range 1-88, median follow-up period 25 months). The procedural complication rate including access-site complications, target lesion perforation, and outflow embolisation was 10.4% (n=26). All but one complication could be treated conservatively or endovascularly. One surgical revision was necessary. Freedom from major adverse events (death, cdTLR, myocardial infarction and major target limb amputation) at 30 days was 99.6%. The rate of cdTLR during follow-up was 13.6% (n=34). A significant improvement of the mean ABI and the RBC was observed. Multivariate logistic regression analysis revealed residual target lesion stenosis >30% (p=0.005), and heavy calcification of the target lesion (p=0.033) to be independent predictors for cdTLR.

Conclusions: The use of DA for the treatment of CFA lesions leads to promising midterm results with an acceptable complication rate.

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atherectomyclaudicationcritical limb ischaemiadrug-eluting balloon
Peripheral interventionsIliac / Femoral / Popliteal
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