2. Department of Cardiology, Heart Center Bonn, University Hospital Bonn, Germany
3. Department of Cardiac and Vascular Surgery, University Hospital Zurich, Switzerland
4. Department of Cardiac and Vascular Surgery, University Hospital Zurich, Switzerland
5. Heart Center, University of Cologne, Germany
6. Heart Center, University of Cologne, Germany
7. Department of Cardiology, Asklepios Clinic St. Georg, Hamburg, Germany
8. Department of Interventional Cardiology, Ospedale San Raffaele Milano, Milan, Italy
9. Ospedale San Raffaele, Milan, Italy
10. Department of Cardiology, Asklepios Clinic St. Georg, Hamburg, Germany
11. Department of Cardiac and Vascular Surgery, University Hospital Zurich, Switzerland
12. Heart Center, University of Cologne, Germany
13. Department of Cardiology, Heart Center Bonn, University Hospital Bonn, Germany
As a public service to our readership, this article - peer reviewed by the Editors of EuroIntervention - has been published immediately upon acceptance as it was received. The content of this article is the sole responsibility of the authors, and not that of the journal or its publishers.
To read the full content of this article, please log in to download the PDF.
Methods and results:We collected 123 consecutive patients that were treated with the Cardioband device and 455 consecutive patients treated with the MitraClip from five experienced European centers. Propensity score matching was performed, resulting in two groups with 93 patients each – with no significant differences regarding baseline demographic parameters – who underwent standardized 2D transthoracic echocardiography with assessment at baseline and clinical follow-up at 12 months. The success rate, defined as a reduction of MR to grade 2 or lower, was high in both groups (MR ≤2: MitraClip: 86%, Cardioband: 77%, p=0.18). The Cardioband was better at reducing heart failure symptoms (NYHA ≤2; 88%) than the MitraClip (75%) procedure (p=0.046) at 12-months follow-up. All-cause rehospitalization and mortality within 12 months were lower in Cardioband patients (mortality: OR 0.30, CI 0.09-0.98, p=0.032; rehospitalization: OR 0.57, CI: 0.28-0.97, p= 0.03).
Conclusions:The MitraClip and the Cardioband procedures effectively reduce MR and heart failure symptoms. However, patients undergoing the Cardioband procedure showed a more pronounced improvement with regard to functional NYHA class, rehospitalization, and mortality, compared to patients undergoing the MitraClip procedure.
Sign in to read and download the full articleForgot your password?
Join us for free and access thousands of articles from EuroIntervention, as well as presentations, videos, cases from PCRonline.com