The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Coronary interventions

In vivo intravascular photoacoustic imaging of plaque lipid in coronary atherosclerosis

EuroIntervention 2019;15:452-456. DOI: 10.4244/EIJ-D-19-00318

1. Department of Cardiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands; 2. Department of Biomedical Engineering, Technical University Eindhoven, Eindhoven, the Netherlands; 3. Department of Experimental Medical Instrumentation, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands; 4. Department of Imaging Physics, Delft University of Technology, Faculty of Applied Sciences, Delft, the Netherlands

Prospective identification of lipid-rich vulnerable plaque has remained an elusive goal. Intravascular photoacoustics, a hybrid optical and ultrasonic technology, was developed as a tool for lipid-rich plaque imaging. Here, we present the first in vivo images of lipid-rich coronary atherosclerosis acquired with this new technology in a large animal model, and relate them to independent catheter-based imaging and histology.

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