Translational research

DOI: 10.4244/EIJ-D-23-00063

Configuration of two-stent coronary bifurcation techniques in explanted beating hearts: the MOBBEM study

Stefano Cangemi1, MD; Francesco Burzotta1,2, MD, PhD; Francesco Bianchini1, MD; Amanda DeVos3, BS; Thomas Valenzuela3, PhD; Carlo Trani1,2, MD; Cristina Aurigemma2, MD, PhD; Enrico Romagnoli2, MD, PhD; Jens Flested Lassen4, MD, PhD; Goran Stankovic5, MD, PhD; Paul Anthony Iaizzo3, PhD

Abstract

Background: In patients with complex coronary bifurcation lesions undergoing percutaneous coronary intervention (PCI), various 2-stent techniques might be utilised. The Visible Heart Laboratories (VHL) offer an experimental environment where PCI results can be assessed by multimodality imaging.

Aims: We aimed to assess the post-PCI stent configuration achieved by 2-stent techniques in the VHL and to evaluate the procedural factors associated with suboptimal results.

Methods: Bifurcation PCI with 2-stent techniques, performed by expert operators in the VHL on explanted beating swine hearts, was studied. The adopted bifurcation PCI strategy and the specific procedural steps applied in each procedure were classified according to Main, Across, Distal, Side (MADS)-2 and to their adherence to the European Bifurcation Club (EBC) recommendations. Microcomputed tomography (micro-CT) was used to assess the post-PCI stent configuration. The primary endpoint was “suboptimal stent implantation”, defined as a composite of stent underexpansion (<90%), side branch ostial area stenosis >50% and the gap between stents.

Results: A total of 82 PCI with bifurcation stenting were assessed, comprised of 29 crush, 25 culotte, 28 T/T and small protrusion (TAP) techniques. Suboptimal stent...

Sign in to read
the full article

Forgot your password?
No account yet?
Sign up for free!

Create my pcr account

Join us for free and access thousands of articles from EuroIntervention, as well as presentations, videos, cases from PCRonline.com

Volume 19 Number 5
Aug 7, 2023
Volume 19 Number 5
View full issue


Key metrics

On the same subject

State-of-the-Art Review

10.4244/EIJ-D-21-01065 Jul 22, 2022
Percutaneous coronary intervention of bifurcation lesions
Hildick-Smith D et al
free

Clinical research

10.4244/EIJ-D-20-00130 Oct 9, 2020
Double-kissing culotte technique for coronary bifurcation stenting
Toth GG et al
free

EXPERT REVIEW

10.4244/EIJ-D-17-00580 Feb 2, 2018
Step-by-step manual for planning and performing bifurcation PCI: a resource-tailored approach
Milasinovic D et al
free

10.4244/EIJV13I15A282 Feb 2, 2018
Keep bifurcation stenting simple and cheap or controlled and optimised?
Holm N et al
free

Translational research

10.4244/EIJ-D-21-00824 May 15, 2022
Bench test and in vivo evaluation of longitudinal stent deformation during proximal optimisation
Toth GG et al
free

Editorial

10.4244/EIJ-E-23-00044 Oct 23, 2023
Shifting focus in bifurcations
Zimarino M et al
free
Trending articles
94.95

State-of-the-Art Review

10.4244/EIJ-D-20-01296 Aug 27, 2021
Management of cardiogenic shock
Thiele H et al
free
56.5

Clinical research

10.4244/EIJ-D-22-00621 Feb 20, 2023
Long-term changes in coronary physiology after aortic valve replacement
Sabbah M et al
free
55.1

Clinical Research

10.4244/EIJ-D-21-00875 Aug 5, 2022
Features of atherosclerosis in patients with angina and no obstructive coronary artery disease
Pellegrini D et al
free
X

The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

EuroPCR EAPCI
PCR ESC
Impact factor: 7.6
2023 Journal Citation Reports®
Science Edition (Clarivate Analytics, 2024)
Online ISSN 1969-6213 - Print ISSN 1774-024X
© 2005-2024 Europa Group - All rights reserved