Rodrigo Bagur1, MD, PhD; Luciano A. Sposato2, MEd, MD
1. Interventional Cardiology, Division of Cardiology, London Health Sciences Centre, Western University, London, Ontario, Canada; 2. Department of Clinical Neurological Sciences; Stroke, Dementia & Heart Disease Laboratory; London Health Sciences Centre; Kathleen and Dr. Henry Barnett Chair in Stroke Research; Western University, London, Ontario, Canada
The prevalence of aortic stenosis (AS) and cognitive impairment increases with age1,2. In the context of a rapidly ageing population3, the number of individuals living with severe AS and dementia is expected to increase worldwide. Cognitive decline is indeed common among individuals with AS4,5. Whether this is due to decreased cardiac output (CO)6, shared risk factors for atherosclerosis7, or a more complex “cardiocerebral continuum”, deserves further discussion.
The uptake of transcatheter aortic valve implantation (TAVI) is rapidly and continuously increasing8. Despite the known efficacy of TAVI on hard outcomes such as death, and stroke9, the association ...