The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Editorial

Antithrombotic therapy in PCI: why not heparin?

EuroIntervention 2013;9:423-426. DOI: 10.4244/EIJV9I4A69

Institute of Cardiovascular Medicine and Science, Liverpool Heart and Chest Hospital, Liverpool, United Kingdom
In this issue of the journal, Schulz and colleagues present new data describing one-year outcomes from the ISAR-REACT 4 trial.

This study recruited patients undergoing PCI in the setting of a non-ST-elevation, acute coronary syndrome presentation. Subjects were randomised to two different periprocedural antithrombotic regimes: bivalirudin or combination therapy with unfractionated heparin (UFH) and abciximab. The reported rates of death, non-fatal myocardial infarction and target vessel revascularisation are near identical.

It is interesting to note that an increased risk of bleeding, observed at 30 days1, in patients receiving abciximab therapy, did not result in differences in key outcome measures at ...

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