The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Editorial

All that glitters is not gold: can videodensitometry replace echocardiography for the assessment of paravalvular aortic regurgitation?

EuroIntervention 2020;15:1219-1222. DOI: 10.4244/EIJV15I14A218

1. Columbia University Medical Center, NY Presbyterian Hospital, New York, NY, USA


The clinical impact of paravalvular regurgitation (PVR) following surgical aortic valve replacement (SAVR) varies depending on the type of valve prosthesis, implant location, and means of delivery. In the aortic position, the incidence of prosthetic PVR is 2%-10%1. A meta-analysis of 12 clinical studies showed that a successful transcatheter closure of PVR (reduction of ≥1 grade) translated into lower cardiac mortality (odds ratio [OR] 0.08, confidence interval [CI]: 0.01-0.9) and greater improvement in New York Heart Association (NYHA) functional class or haemolysis (OR 9.95, CI: 2.1-66.7) with fewer repeat operations (OR 0.08, CI: 0.01-0.4)2. A random effects meta-analysis (including 604 patients from five observational ...

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