The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)


Ruptured and healed atherosclerotic plaques: breaking bad?

EuroIntervention 2019;15:e742-e744. DOI: 10.4244/EIJV15I9A138

1. Department of Cardiology, Institut Mutualiste Montsouris, Paris, France

The evolution of coronary atherosclerosis is not a long quiet river, but rather follows a tumultuous flow. The growth of plaque is a dynamic phenomenon that is not only related to linear volume increase due to progressive lipid accumulation, fibrosis and inflammation but is also marked by episodes of sudden instability, mostly created by atherothrombotic acute episodes1. As a consequence, patients could alternate between long stable clinical periods and acute events, i.e., chronic and acute coronary syndromes (ACS)2. These latter events are essentially induced by symptomatic plaque rupture or erosion. However, pathology studies have strongly suggested that some ...

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