We appreciate the interest of Veulemans and colleagues1 in our article “Impact of horizontal aorta on procedural and clinical outcomes in second-generation transcatheter aortic valve implantation”2.
In their letter, three main remarks can be outlined, for which we provide the following comments.
1. The previously established threshold to define horizontal aorta (HA) for first-generation valves (aortic angulation [AA] ≥48°) as proposed by Abramowitz et al3 should be adjusted to current prosthesis generations and even further to several device sizes.
We addressed this issue in the paper by assessing the association of the AA as ...
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