Original Research

DOI: 10.4244/EIJ-D-23-00406

Ostial right coronary artery lesion morphology and outcomes after treatment with drug-eluting stents

Kei Yamamoto1,2, MD; Takao Sato1,2, MD; Hanan Salem1,2,3, MD; Yu-Wei Chen1,2, MD; Mitsuaki Matsumura2, BS; Nikolas Bletnitsky1, BS; Khady N. Fall1, MD, MPH; Megha Prasad1, MD, MS; Vivian G. Ng1, MD; Sanjum S. Sethi1, MD; Tamim M. Nazif1,2, MD; Sahil A. Parikh1,2, MD; Torsten P. Vahl1,2, MD; Ziad A. Ali2,4, MD, DPhil; Dimitri Karmpaliotis2,5, MD, PhD; LeRoy E. Rabbani1,2, MD; Michael B. Collins1, MD; Martin B. Leon1,2, MD; Margaret McEntegart1,2, MD, PhD; Jeffery W. Moses1,2,4, MD; Ajay J. Kirtane1,2, MD, SM; Gary S. Mintz2, MD; Akiko Maehara1,2, MD


BACKGROUND: Outcomes after percutaneous coronary intervention (PCI) for de novo ostial right coronary artery (RCA) lesions are poor.

AIMS: We used intravascular ultrasound (IVUS) to clarify the morphological patterns of de novo ostial RCA lesions and their associated clinical outcome.

METHODS: Among 5,102 RCA IVUS studies, 170 de novo ostial RCA stenoses (within 3 mm from the aorto-ostium) were identified. These were classified as 1) isolated ostial lesions (no disease extending beyond 10 mm from the ostium and without a calcified nodule [CN]); 2) ostial CN, typically with diffuse disease (disease extending beyond 10 mm); and 3) ostial lesions with diffuse disease but without a CN. The primary outcome was target lesion failure (TLF: cardiac death, target vessel myocardial infarction, definite stent thrombosis, and ischaemia-driven target lesion revascularisation).

RESULTS: The prevalence of an isolated ostial lesion was 11.8% (n=20), 47.6% (n=81) were ostial CN, and 40.6% (n=69) were ostial lesions with diffuse disease. Compared to ostial lesions with diffuse disease, isolated lesions were more common in women (75.0% vs 42.0%; p=0.01), and CN were associated with older age...

Sign in to read
the full article

Forgot your password?
No account yet?
Sign up for free!

Create my pcr account

Join us for free and access thousands of articles from EuroIntervention, as well as presentations, videos, cases from PCRonline.com

Volume 20 Number 3
Feb 5, 2024
Volume 20 Number 3
View full issue

Key metrics

On the same subject

Clinical research

10.4244/EIJ-D-23-00107 Aug 7, 2023
Mechanisms and treatment outcomes of ostial right coronary artery in-stent restenosis
Yamamoto K et al

Clinical Research

10.4244/EIJ-D-21-00504 Mar 18, 2022
Prevalence, predictors, and outcomes of in-stent restenosis with calcified nodules
Tada T et al


10.4244/EIJ-E-22-00053 Feb 20, 2023
Coronary calcification: you have to crack a few eggs to make an omelette
Sabaté M


10.4244/EIJ-E-23-00007 Apr 24, 2023
Percutaneous coronary interventions for ostial left main disease: the future is bright
Chieffo A and Beneduce A


10.4244/EIJ-E-23-00002 Jun 5, 2023
All calcified nodules are made equal and require the same approach: pros and cons
Guagliumi G et al
Trending articles

State-of-the-Art Review

10.4244/EIJ-D-21-01034 Jun 3, 2022
Management of in-stent restenosis
Alfonso F et al

Translational research

10.4244/EIJ-D-21-00824 May 15, 2022
Bench test and in vivo evaluation of longitudinal stent deformation during proximal optimisation
Toth GG et al

Expert review

10.4244/EIJ-D-21-00690 May 15, 2022
Crush techniques for percutaneous coronary intervention of bifurcation lesions
Moroni F et al


10.4244/EIJ-D-22-00776 Apr 3, 2023
Computed tomographic angiography in coronary artery disease
Serruys PW et al


10.4244/EIJ-E-22-00007 May 15, 2022
TAVI at 20: how a crazy idea led to a clinical revolution
Eltchaninoff H et al

The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

Impact factor: 6.2
2022 Journal Citation Reports®
Science Edition (Clarivate Analytics, 2023)
Online ISSN 1969-6213 - Print ISSN 1774-024X
© 2005-2024 Europa Group - All rights reserved