The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Technical report

Non-invasive fractional flow reserve: scientific basis, methods and perspectives

EuroIntervention 2012;8:511-519 published online ahead of print May 2012. DOI: 10.4244/EIJV8I4A79

Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands

In 2008, our group investigated the accuracy of quantitative measurements for lumen, vessel and plaque volume derived from multislice computed tomography (MSCT) scans in comparison with intravascular ultrasound (IVUS) greyscale in a cohort of 47 patients: an excellent correlation and a relatively acceptable agreement were shown1. More recently, Voros and colleagues reviewed the field and published a comprehensive analysis of the relationship between MSCT- and IVUS-derived measures for lumen and plaque area2. They concluded that for lumen and vessel areas good correlations exist with a coefficient higher than 0.7, and a systematic error of about 20%, MSCT values being consistently overestimated. Regarding ...

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