Thomas Modine1,2, MD, PhD, MBA; Bernard D. Prendergast3, PhD, MD, FRCP, FESC; Nicolo Piazza4, MD; Pavel Overtchouk5, MD
1. Cardiology and Cardiovascular Surgery Department, Heart Valve Center, Institut Cœur Poumon CHU de Lille, Lille, France; 2. Jiao Tong University School of Medicine, Shanghai, China; 3. Department of Cardiology, St Thomas’ Hospital, London, United Kingdom; 4. Interventional Cardiology, McGill University Health Centre, Montréal, Canada; 5. Department of Cardiology, Bern University Hospital, Bern, Switzerland
Mitral regurgitation: a clinical challenge
A 75-year-old patient was suffering from debilitating dyspnoea due to severe degenerative mitral regurgitation (MR) responsible for left ventricle enlargement. The Heart Team estimated that the patient was inoperable due to excessive surgical risk. The patient was treated with transcatheter percutaneous edge-to-edge intervention in accordance with current international guidelines1,2. After implantation of two clips, the transmitral mean gradient was 7 mmHg and residual MR was moderate. Should this patient have been considered for transcatheter mitral valve replacement (TMVR) instead of repair?
MR is present in >1% of the Western population over 70 years old, ...