The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

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Indications, current adoption and future perspectives for percutaneous left atrial appendage closure

EuroIntervention 2019;14:1707-1709. DOI: 10.4244/EIJV14I17A293

The Heart Center, Rigshospitalet, Copenhagen, Denmark


Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice and an independent risk factor for ischaemic stroke. It is estimated that AF is present in approximately 1-2% of the total population, although this number may be as high as 5-10% in those aged more than 70years. In addition, it is foreseen that the prevalence of AF will triple in the western world in the next four decades. As aconsequence, stroke prevention in AF patients is amajor public health priority.

Traditionally, vitamin K antagonists (e.g., warfarin) have been used as oral anticoagulant (OAC) therapy ...

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