The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

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In vivo delivery and long-term tissue retention of nano-encapsulated sirolimus using a novel porous balloon angioplasty system

EuroIntervention 2016;12:740-747 published online ahead of print October 2015. DOI: 10.4244/EIJY15M10_01

1. CRF-Skirball Center for Innovation, Orangeburg, New York, NY, USA; 2. Alizee Pathology, Thurmont, MD, USA; 3. Caliber Therapeutics, New Hope, PA, USA; 4. Columbia University Medical College, New York, NY, USA

Aims: Among antirestenotic compounds, sirolimus displays a superior safety profile compared to paclitaxel, but its pharmacokinetic properties make it a challenging therapeutic candidate f

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