The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)
Experimental research
In vivo assessment of the relationship between shear stress and necrotic core in early and advanced coronary artery disease
EuroIntervention 2013;9:989-995 published online ahead of print March 2013. DOI: 10.4244/EIJV9I8A165
Jolanda J. Wentzel1,4*, PhD; Johan C.H. Schuurbiers1, BSc; Nieves Gonzalo Lopez2, MD; Frank J.H. Gijsen1, PhD; Alina G. van der Giessen1, PhD; Harald C. Groen1, PhD; Jouke Dijkstra3, PhD; Hector M. Garcia-Garcia2, PhD; Patrick W. Serruys2, MD, PhD
1. Biomedical Engineering, ErasmusMC, Rotterdam, The Netherlands; 2. Interventional Cardiology, ErasmusMC, Rotterdam, The Netherlands; 3. LKEB, Department of Radiology, Leiden University Medical Centre, Leiden, The Netherlands; 4. Int
Aims: Atherosclerotic plaques develop at low shear stress locations in the arterial tree. However, at a certain moment, plaques encroach into the lumen causing local wall shear stress