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First-in-human experience: percutaneous renal denervation through a false lumen fenestration in aortic dissection type B

EuroIntervention 2013;8:1110. DOI: 10.4244/EIJV8I9A170

Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany
A 61-year-old man (height 181 cm, weight 110 kg) presented to our clinic with dyspnoea (NYHA Class II) and progressive chest and abdominal pain. Medical history included an aortic dissection type B with perfusion of the left kidney from the false lumen, diagnosed in 2009 (Figure 1A and Figure 1B). The patient was receiving five antihypertensive drugs (bisoprolol 5 mg ½-0-½, hydrochlorothiazide 25 mg 1-0-0, amlodipine 10 mg 1-0-0, urapidil 90 mg 1-0-1, moxonidine 0.3 mg 1-0-1). Office blood pressure (BP) was 160/95 mmHg. Ambulatory 24-hour BP monitoring confirmed true treatment resistance (mean 141/91 mmHg, non-dipping pattern).

Figure 1. A) Magnetic resonance angiography (MRA) ...

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