Early invasive approach and outcome in elderly patients with NSTEACS: randomised trials, real-world data and guideline recommendations

EuroIntervention 2021;17:20-21. DOI: 10.4244/EIJV17I1A4

Stefano Savonitto
Stefano Savonitto1, MD, FESC; Stefano De Servi2, MD, FESC
1. Cardiovascular Department, Manzoni Hospital, Lecco, Italy; 2. University of Pavia, Pavia, Italy
Patients older than 75 years represent about 40% of coronary care unit admissions with non-ST-elevation acute coronary syndromes (NSTEACS)1; however, they have been underrepresented in randomised clinical trials (RCTs). Only during the last decade have dedicated RCTs compared an early invasive (EI) with an initially conservative (IC) approach in elderly patients2,3,4. The first of these, the Italian Elderly ACS randomised trial, enrolled 313 NSTEACS patients aged ≥75 years and found a reduction with EI treatment in the composite primary 12-month endpoint (mortality, non-fatal myocardial infarction [MI], disabling stroke and readmission for cardiovascular causes or bleeding) in patients with elevated troponin (Tn) levels (60% of ...

Sign in to read and download the full article

Forgot your password?

No account yet?
Sign up for free!

Create my pcr account

Join us for free and access thousands of articles from EuroIntervention, as well as presentations, videos, cases from PCRonline.com

Read next article
EAPCI Core Curriculum for Percutaneous Cardiovascular Interventions (2020): Committee for Education and Training European Association of Percutaneous Cardiovascular Interventions (EAPCI). A branch of the European Society of Cardiology.

Latest news