Coronary interventions

Correlation of near-infrared spectroscopy, optical coherence tomography and post-mortem histology for lipid detection

EuroIntervention 2021;16:e1529-e1530. DOI: 10.4244/EIJ-D-19-00775

Christian Zanchin
Christian Zanchin1; Lucine Christe2; Lorenz Räber1
1. Department of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland; 2. Institute of Pathology, University of Bern, Bern, Switzerland

Figure 1. Matched near-infrared spectroscopy and optical coherence tomography cross-sections with post-mortem histopathology specimens. A1) & B1) Angiography of the LAD and RCA, respectively. A2) & B2) NIRS chemogram of the LAD and RCA, respectively. The red line indicates where lipid accumulation was maximal according to the NIRS-derived chemogram within the maxLCBI4mm segment and where matching with OCT and post-mortem histology was performed. A3) & B3) Matched IVUS-NIRS, OCT and post-mortem histology cross-sections. The asterisk marks the lipid pool. The arrow points to the calcium to confirm appropriate matching. Histopathology specimen confirmed NIRS-detected lipid behind the calcium, which ...

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