Comparison of pressure wire versus microcatheter for fractional flow reserve measurements: limitations of microcatheter-based measurements

EuroIntervention 2019;14:1703-1704. DOI: 10.4244/EIJ-D-18-00338L

Ozan Demir
Ozan M. Demir1,2, MBBS; Satoru Mitomo1, MD; Francesco Giannini1, MD; Antonio Colombo1, MD; Azeem Latib1*, MD
1. IRCCS San Raffaele Scientific Institute, Milan, Italy; 2. Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

We read with great interest the recent paper by Pouillot et al1, assessing the clinical impact of the new fractional flow reserve (FFR) microcatheter (Navvus™ MicroCatheter; ACIST Medical Systems, Inc., Eden Prairie, MN, USA). Seventy-seven consecutive patients were recruited into a prospective registry and had FFR evaluated by microcatheter (FFRMC) and by pressure wire (FFRW). The authors reported that the mean FFRW (0.83±0.08) was significantly higher than the mean FFRMC (0.80±0.10) (p=0.012) and that the Bland-Altman analysis showed a bias of –0.03±0.05 for lower FFRMC values compared to FFRW values. The Pearson’s correlation coefficient (r) between FFRW and FFRMC was 0.85 (p&...

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